Project Description

About the project of Fabio

The aim of my project is to evaluate the ability of active biomolecules and growth factors, delivered by nanocarriers, to induce cartilage formation and repair in vitro and in murine models. My work is also focused on the molecular analysis of activation and rectruitment of the endogenous stem/progenitor cells to the damaged tissue, evaluating their contribution to tissue repair and potential for therapeutic intervention in osteoarthritis. In order to achieve these goals, a wide range of techniques are involded, such as stem cell culture, transgenic approaches, histochemistry, immunofluorescence with laser-scanning confocal microscopy and in vivo imaging.