About the project
For many patients with chronic low back pain or osteoarthritis, mobility – and thereby well-being – is seriously impaired. This is due to degeneration of cartilaginous tissue of intervertebral discs (IVD) and joints. The TargetCaRe consortium aims to develop treatments for these diseases by combining advanced drug delivery carriers with dedicated targeting tools, state of the art imaging techniques and expertise in biology of stem cells and joints. The research will be conducted by 15 young scientists, or Early Stage Researchers (ESRs).
The TargetCaRe consortium aims both to prevent further degradation of a damaged joint or IVD, as well as to activate the body’s own regenerative capacity to heal damaged and degenerated tissues in the joint and the IVD. To achieve this, therapeutical molecules will be delivered to the joint or IVD by so-called nanocarriers. Targeting strategies will be developed to ensure that the nanocarriers containing therapeutical molecules will get to the damaged tissue in the joint or IVD after injection. High tech imaging methods will be used to monitor the delivery of the nanocarriers and the effect of the therapeutic molecules on the damaged joint or IVD tissue.
More information on TargetCaRe research can be found on the ESR pages, containing descriptions of the individual research projects of each ESR.
TargetCaRe: a Marie Sklodowska Curie Action – International Training Network
One of the main objectives of the TargetCaRe consortium, being an International Training Network, is to establish a network of ESRs trained in the various TargetCaRe technologies. Each ESR will set up a personal career development plan (PCDP) that describes the individual learning goals and personal vision on the ESRs career. The dedicated and excellent training programme for all ESRs will consist of:
- Research at their home institutions and during secondments at the premises of consortium partners
- Lectures and workshops in TargetCaRe technologies, covering subjects such as nanomedicine, stem cell joint and intervertebral disc biology and in vivo imaging
- Training in valorization, communication and regulatory issues provided by our non-academic partners
- A tailored selection courses and trainings to enable optimal personal and professional development of each ESR
For more information on Horizon 2020 Marie Sklodowska Curie Actions, please visit the MSCA website of the European Commission.